Over The Rhine leader Linford Detweiler is as quiet and mellow as Afghan Whigs frontman Greg Dulli is brash and prickly. But Mr. Detweiler says the two Cincinnati musicians have a lot in common. ‘‘We’re starting to experience that Whigs syndrome a little bit,’’ Mr. Detweiler says from a Dubuque, Iowa, tour stop, echoing Mr. Dulli’s complaints about local apathy. ‘There seems to be more of a freshness and excitement about the band elsewhere. We sold out two nights in Seattle; had our biggest crowd ever in Minneapolis. It’s starting to spread out more, and the hometown crowd, it’s hard to impress them.’’ Well, Saturday’s show at the Taft ought to do it. Along with OTR, the band’s annual holiday homecoming features two opening acts — Sixpence None the Richer and singer/songwriter Ron Sexsmith (7:30 p.m., $14 at the Taft box office and Ticketmaster; 562-4949). ‘‘That’s our one show a year where we really try to be fans for an evening — bring in people we want a chance to hear and hang out with a little bit.’’ Nonetheless, the show is not sold out, even as the Cincinnati-based band’s national profile continues to rise. On Feb. 27, OTR will release a new studio album on Backporch/Virgin. Some of that material will be debuted Saturday. The group will feature Mr. Detweiler on keyboards and his wife, Karin Bergquist, on vocals and guitar. Jack Henderson continues on guitar and lap steel. Terri Templeton returns on vocals; the rhythm section will be bassist Wade Jaynes and Sixpence drummer Dale Baker. Like Mr. Dulli did years ago, Mr. Detweiler is considering relocating, with Nashville and Toronto topping the list. ‘‘We tend to get a bit more inspired when we go over the horizon,’’ he says. For now, he’s looking forward to returning the couple’s home in Norwood. He promises some surprises Saturday, including something that will be a surprise even to him. ‘‘Karin’s got one tucked up her sleeve that she’s not telling anyone about,’’ he says.